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Acts70th Leg. Amended by Acts77th Leg. Acts79th Leg.

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Guidelines under this paragraph shall require- " A the appropriate use of tranquilizers, analgesics, anesthetics, paralytics, and euthanasia for animals in such research; and " B appropriate pre-surgical and post-surgical veterinary medical and nursing care for animals in such research.

Such guidelines shall not be construed to prescribe methods of research. Reports filed under subparagraph C shall include any minority views filed by members of the committee.

Notwithstanding subsection a 2 of section of title 5, United States Code, regulations under this subsection shall be promulgated in accordance with the notice and comment requirements of such section. Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training The development of knowledge necessary for the improvement of the health and well-being of humans as well as other animals requires in vivo experimentation with a wide variety of animal species.

Government agencies develop requirements for testing, research, or training procedures involving the use Government required service vertebrate animals, the following principles shall be considered; and whenever these agencies actually perform or sponsor such procedures, the responsible Institutional Official shall ensure that these principles are adhered to: The transportation, care, and use of animals should be in accordance with the Animal Welfare Act 7 U.

The animals selected for a procedure should be of an appropriate species and quality and the minimum number required to obtain valid results.

Methods such as mathematical models, computer simulation, and in vitro biological systems should be considered. Proper use of animals, including the avoidance or minimization of discomfort, distress, and pain when consistent with sound scientific practices, is imperative.

Unless the contrary is established, investigators should consider that procedures that cause pain or distress in human beings may cause pain or distress in other animals.

Procedures with animals that may cause more than momentary or slight pain or distress should be performed with appropriate sedation, analgesia, or anesthesia. Surgical or other painful procedures should not be performed on unanesthetized animals paralyzed by chemical agents.

Animals that would otherwise suffer severe or chronic pain or distress that cannot be relieved should be painlessly killed at the end of the procedure or, if appropriate, during the procedure. The living conditions of animals should be appropriate for their species and contribute to their health and comfort.

Normally, the housing, feeding, and care of all animals used for biomedical purposes must be directed by a veterinarian or other scientist trained and experienced in the proper care, handling, and use of the species being maintained or studied. In any case, veterinary care shall be provided as indicated.

Investigators and other personnel shall be appropriately qualified and experienced for conducting procedures on living animals.

(Federal Acquisition Regulation Site)

Adequate arrangements shall be made for their in-service training, including the proper and humane care and use of laboratory animals. Where exceptions are required in relation to the provisions of these Principles, the decisions should not rest with the investigators directly concerned but should be made, with due regard to Principle II, by an appropriate review group such as an institutional animal care and use committee.

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Such exceptions should not be made solely for the purposes of teaching or demonstration. Introduction It is the Policy of the Public Health Service PHS to require institutions to establish and maintain proper measures to ensure the appropriate care and use of all animals involved in research, research training, and biological testing activities hereinafter referred to as "activities" conducted or supported by the PHS.

The PHS endorses the "U.

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CHAPTER MUNICIPAL CIVIL SERVICE FOR FIREFIGHTERS AND POLICE OFFICERS The director shall serve as secretary to the commission and perform work incidental to the civil service system as required by the .

GPO Style Manual: An Official Guide to the Form and Style of Federal Government Publishing (Paperback) United States Government Publishing Office Style Manual Paperback Title.

required service, and get industry feedback on your working documents. Finally, synthesize an acquisition strategy that leverages contract type and performance incentives to deliver a best value mission performance to the customer.

This guide is intended to assist departments with managing their responsibilities on nationality rules related to Civil Service recruitment. Government efficiency, transparency and. Subpart S Official Use of Government Vehicles.

Required at the beginning or close of a day to initiate, continue, or complete official travel. (b) Delegation. Commissioner, Regional Directors, and the Reclamation Service Center (RSC) Director are delegated authority to authorize an employee's use of a Government-owned or -leased.

U.S. Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training Public Health Service - The Public Health Service, or the PHS, D. Information Required in Applications and Proposals for Awards Submitted to the PHS. 1. All Institutions.

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